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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone regeneration in calvarial bone defects

Fig. 4

Effect of melatonin (0, 100, 10, and 1 μM) on ALP activity of DPSCs at 1 and 3 days after incubation with and without osteogenic differentiation medium. a Melatonin at 100 μM significantly enhanced ALP activity of DPSCs with osteogenic differentiation medium after 1 day of culture. b Melatonin at 100, 10, and 1 μM significantly enhanced ALP activity of DPSCs with osteogenic differentiation medium after 3 days of culture. (ALP alkaline phosphatase, GM growth medium, OM osteogenic medium, Mel melatonin) (*p < 0.05, **p < 0.01)

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Stem Cell Research & Therapy

ISSN: 1757-6512