|
No.21
|
Standard prophylaxis group:30y (18–60) Standard prophylaxis + MSCs group:37y (20–63)
|
1
|
1 × 106/kg
|
100d grade II–IV aGVHD:Standard prophylaxis group:29.4 Standard prophylaxis + MSCs group:9.4 p = 0.041
|
N/A
|
exact time unknown:Standard prophylaxis group:61.8 Standard prophylaxis + MSCs group:81.2 p < 0.05
|
N/A
|
Kuzmina et al. [42]
|
|
No.21
|
34y (17–63)
|
1
|
1.2 (0.9–1.65) × 106/kg
|
100d grade II–IV aGVHD:Standard prophylaxis group:20.5 Standard prophylaxis + MSCs group:10.2
|
N/A
|
N/A
|
N/A
|
Shipounova et al. [43]
|
|
No.34
|
MSC group:58y (21–69) historic group:55y (10–69)
|
1
|
N/A
|
100d grade II–IV aGVHD:MSC group:35 historic group:56 grade IV aGVHD:MSC group:10 historic group:19
|
1y moderate/severe cGVHD:MSC group:65
|
1y:MSC group:80 historic group:44 p = 0.02
|
560d
|
Baron et al. [93]
|
|
No.38
|
MSC group:6.9y (3.3–12.5) historic group:9.5y (8.4–18.7)
|
1
|
1/5 × 106/kg
|
grade I–II aGVHD:MSC group:57.1 historic group:62.5 p = 0.83 grade III–IV aGVHD:MSC group:14.3 historic group:0 p = 0.36
|
extensive cGVHD:MSC group:14.3 historic group:50.0 p = 0.27
|
2y:MSC group:85.7 historic group:55.6 p = 0.15
|
N/A
|
Lee et al. [94]
|
|
No.60
|
N/A
|
3.7 (2–4)
|
3 × 107/100 mL/m
|
N/A
|
2y:MSC group:27.4 control group:49.0 p = 0.021
|
2y:MSC group:66.1 historic group:61.3 p > 0.05
|
51m
|
Gao et al. [92]
|
