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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Comparison of two cell-free therapeutics derived from adipose tissue: small extracellular vesicles versus conditioned medium

Fig. 4

sEV-AT and ATE promoted angiogenesis of HUVEC. A Growth curves showed the proliferation of HUVEC that co-cultured with sEV-AT or ATE. B Scratch test showed the migration of HUVEC that co-cultured with sEV-AT or ATE. C Quantification of HUVEC migration. D Tube formation assay showed the angiogenesis of HUVEC that co-cultured with sEV-AT or ATE. E Quantification of angiogenesis with number of nodes, number of junctions and total length. F Real-time PCR showed the expression of angiogenesis-related genes in HUVEC that co-cultured with sEV-AT or ATE. Data were represented as mean ± SEM. n = 3. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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