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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Comparison of two cell-free therapeutics derived from adipose tissue: small extracellular vesicles versus conditioned medium

Fig. 5

sEV-AT and ATE promoted the chemoattraction ability of RAW264.7. A Growth curves showed the proliferation of macrophages that co-cultured with sEV-AT or ATE. B Scratch test showed the migration of macrophages that co-cultured with sEV-AT or ATE. C Quantification of RAW264.7 migration. D, E chemoattraction of sEV-AT or ATE treated RAW264.7 on RAW 264.7 and the relative quantification. F, G chemoattraction of sEV-AT or ATE treated RAW264.7 on ASCs and the relative quantification. H, I chemoattraction of sEV-AT or ATE treated RAW264.7 on HUVECs and the relative quantification. J Real-time PCR showed the expression of cytokine in RAW 264.7 co-cultured with sEV-AT or ATE. Data were represented as mean ± SEM. n = 3. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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