Fig. 7

A sheet of rCPSCs with Mfn2 over-expression ameliorated cartilage damage in a rat OA model. A, B Histological evaluation using Safranin O/ fast green and HE staining of knee joints sections from the four groups. Bar = 500 and 100 µM, 10 rats per group. D, E Modified Mankin and OARSI score system used to evaluate the four groups. C, F TUNEL staining for the cartilage of the four groups. Bar = 200 µM. *P less than 0.05. OE over-expression of Mfn2, OE-NC negative control group of Mfn2 over-expression. OA = osteoarthritis, TUNEL = terminal deoxynucleotidyl transferase dUTP nick end labeling