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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian insufficiency (POI)

Fig. 3

SDF-1 induces hAD-MSC migration in vitro. a, b The migration of hAD-MSCs was tested by performing a Transwell migration assay with 0, 50, 100 or 150 ng/mL SDF-1 in vitro (×200). c, d The role of the SDF-1/CXCR4 axis in the SDF-1-induced migration of hAD-MSCs was detected by performing a Transwell migration assay. The migration of hAD-MSCs was tested in the control, SDF-1, SDF-1 + AMD3100 and AMD3100 groups (×200). Representative images are shown. N = 6, *P < 0.05 and **P < 0.01. Scale bars = 50 μm

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