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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian insufficiency (POI)

Fig. 6

Effects of hAD-MSCs on ovarian function in rats with chemotherapy-induced POI after blocking the SDF-1/CXCR4 axis. a Oestrous cycles of rats were observed. Regular oestrous cycles consisted of 4 sequential stages: proestrus, oestrus, metoestrus and dioestrus (×40). b The percentages of rats with abnormal cyclicity were detected at 1, 3, and 6 weeks after cell transplantation. c–e Serum levels of AMH (c), FSH (d) and E2 (e) were detected at 0, 3 and 6 weeks after cell transplantation. Representative images are shown. *P < 0.05 and **P < 0.01. Scale bars = 100 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512