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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian insufficiency (POI)

Fig. 9

Effects of the PI3K/Akt signalling pathway on the migration of hAD-MSCs mediated by the SDF-1/CXCR4 axis. The migration of hAD-MSCs was tested using the Transwell migration assay (a), and the number of migrated cells was counted (b) in the control, SDF-1, SDF-1 + LY294002 and LY294002 groups under a microscope (×100). Representative images are shown. N = 6, *P < 0.05 and **P < 0.01. Scale bars = 100 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512