Fig. 3

Inflammatory parameters. Levels of inflammatory cytokines, TNF-α or IL-6 did not show any significant changes at the follow up visits compared to baseline (a, b). No significant changes were seen in either ESR or CRP levels (c, d). Significance defined at p value ≤ 0.01 (Holm–Šídák correction for multiple comparisons); Wilcoxon-signed rank test