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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246

Fig. 3

SHED-Exos suppress the migration of endothelial cells. A Wound healing assay demonstrating the significantly decreased closure of the scratch area in the SHED-Exos-treated group compared with the control group. Scale bars = 200 μm. B Quantification of the rate of scratch closure (%) in A. C Transwell migration assays revealing that a significantly lower number of HUVECs migrated through membranes with SHED-Exos than with PBS. Scale bars = 200 μm. D Quantification of the number of migrated cells per field in C. P values are indicated with *, * Indicates P < 0.05, ** indicates P < 0.01, *** indicates P < 0.001, when comparing SHED-Exos-treated cells with the controls in B and D by Student’s t test

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