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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Small extracellular vesicles from dental follicle stem cells provide biochemical cues for periodontal tissue regeneration

Fig. 7

DFSCs-sEVs promoted periodontal tissue regeneration in rats. A In vivo experiment design. B In vivo location of DFSCs-sEVs. Cell nuclei were stained with DAPI (blue), and DFSCs-sEVs were labelled with PKH26 (red). The white arrows show the DFSCs-sEVs. C Quantification of DFSCs-sEVs. D Representative micro-CT reconstruction images showing new bone formation in different groups at 2–8 weeks. E Quantitative micro-CT assessment of BV/TV (%), Tb.Th (mm). F Histological evaluation of periodontal regeneration. CS, collagen sponges; nb, new bone; nPDL, new periodontal ligament; d: dentin. *p < 0.05; **p < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512