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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Increased phosphatase regenerating liver-1 trigger vascular remodeling in injured ovary via platelet-derived growth factor signaling pathway

Fig. 2

Effect of transplanted PRL-1-overexpressing cells on the PDGF signaling pathway in the ovaries of OVX rats. a The concentration of VEGF in serum was analyzed by ELISAs. b The protein expression of PDGFRα and c PDGFRβ was analyzed by western blots. d The localization and gene expression of PDGFRβ in arteries and follicles of ovarian tissues were analyzed by immunohistochemistry staining. e The PDGFRβ intensity of arteries and f mature follicles in the ovary was analyzed by the 3D HISTECH program. The data are representative of three independent experiments and expressed as the means ± S.D. *p < 0.05, normal versus NTx, NTx versus Tx (Naïve and PRL-1), and Naïve versus PRL-1 at each time point

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Stem Cell Research & Therapy

ISSN: 1757-6512