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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Increased phosphatase regenerating liver-1 trigger vascular remodeling in injured ovary via platelet-derived growth factor signaling pathway

Fig. 5

Effect of transplanted PRL-1-overexpressing cells on ovarian function in OVX rats. a The levels of AMH, b estrogen, c FSH and d testosterone in individual serum samples were analyzed by ELISAs. e The gene expression of Nobox, f BMP15 and g EGFR in the ovary was analyzed by western blots. h Histological analysis of follicular development was analyzed by H&E staining. Scale bar: 1 mm, magnification: 1.4×. i The percentage of follicles according to follicular development was analyzed by the 3D HISTECH program. The data are representative of three independent experiments and expressed as the mean ± S.D. *p < 0.05, normal versus NTx, NTx versus Tx (Naïve and PRL-1), and Naïve versus PRL-1 at each time point

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