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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Increased phosphatase regenerating liver-1 trigger vascular remodeling in injured ovary via platelet-derived growth factor signaling pathway

Fig. 6

Effect of PRL-1-overexpressign cells on follicular development via the PDGF pathway ex vivo. a The mRNA expression of hAlu, b human PRL-1, c PDGF-BB, d PDGFRβ, e Nobox and f Lhx8 in ovaries with siRNA-PRL-1 was analyzed by qRT-PCR. g The mRNA expression of PDGF-BB, h PDGFRβ, i VEGF and VEGFR2 in ovaries treated with recombinant PDGF and inhibitor was analyzed by qRT-PCR. The data are representative of three independent experiments and expressed as the mean ± S.D. *p < 0.05, normal versus NTx, NTx versus Tx (Naïve and PRL-1), Naïve versus PRL-1 at each time point

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