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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Adipose-derived stem cells ameliorate atopic dermatitis by suppressing the IL-17 expression of Th17 cells in an ovalbumin-induced mouse model

Fig. 3

Effect of ADSCs on gene expression level of proinflammatory cytokines in OVA-induced AD mice. Relative gene expression levels of a IL-13, b IL-4, c IL-4R, d IL-17A, e CCL20, f MMP12, g IFN-γ and h TNF-α in the skin lesions measured by qPCR. n = 6 per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. NC, normal control; PBS, phosphate-buffered saline; ADSC, adipose-derived stem cell; AD, atopic dermatitis; OVA, ovalbumin; qPCR, quantitative real-time polymerase chain reaction; COR, cortisone; IL, interleukin; IL-4R, IL-4 receptor; CCL20, C–C motif chemokine ligand 20; MMP12, matrix metallopeptidase 12; IFN-γ, interferon-gamma; TNF-α, tumor necrosis factor-alpha

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Stem Cell Research & Therapy

ISSN: 1757-6512