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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Effect of small extracellular vesicles derived from IL-10-overexpressing mesenchymal stem cells on experimental autoimmune uveitis

Fig. 3

Treatment with sEV-IL10 results in a significant reduction in the infiltration of Th1 and Th17 cells in the eye, whereas in an increment of Treg cells in the spleen and draining lymph nodes. A–C Flow cytometric analysis of CD4 + IFN-γ + and CD4 + IL17A + cells in the eyeball from each group. D–I Flow cytometric analysis of Th1 (CD4 + IFN-γ +) and Th17 (CD4 + IL17A +) cells in the draining lymph nodes and spleen from each group. G–L Flow cytometric analysis of CD4 + FOXP3 + cells in the draining lymph nodes and spleen from each group. Mean ± SD, n = 6 per group, one-way ANOVA test. ***P < 0.01, *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512