Fig. 4
Forest plot of RCS changes before and after treatment with MSCs. Only two studies comparison of RCS value and they were significant heterogeneity (I2 = 93%). Hence, a random-effects model was used for analysis and no significant difference was observed at 6 months (P > 0.05). In the plane rectangular coordinate system, the forest plot takes a vertical invalid line (scale of abscissa is 0) as the center, describes the effect quantity and 95% CI of each study by using multiple line segments parallel to the horizontal axis, and describes the effect quantity and confidence interval of multiple studies by using a diamond. RCS, Raynaud's condition score; MSCs, mesenchymal stem cells; CI, confidence interval; SMD, standardized mean difference