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Table 4 Comparison of the WOMAC total score before and after treatment in the SVF and the control group

From: Mid-term prognosis of the stromal vascular fraction for knee osteoarthritis: a minimum 5-year follow-up study

Before or after treatment

Group

Pre-treatment

1 year

2 years

3 years

5 years

Sum

F

p value

SVF

33.24 ± 21.93

18.02 ± 18.87***

20.57 ± 20.13**

23.14 ± 21.03*

27.04 ± 22.47ns

24.40 ± 21.43

36.195

 < 0.001

HA

28.44 ± 18.23

28.27 ± 21.07ns

31.28 ± 22.33ns

33.36 ± 22.88ns

36.05 ± 22.52ns

31.48 ± 21.54

46.619

 < 0.001

Sum

30.57 ± 20.00

23.72 ± 20.68

26.53 ± 21.95

28.83 ± 22.57

32.05 ± 22.85

28.34 ± 21.7a

45.087a

 < 0.001a

F

1.449

6.609

7.015

6.378

5.108

3.335a

(F = 41.307

p value < 0.001)b

p value

0.229

0.010

0.008

0.012

0.024

0.070a

  1. SVF, stromal vascular fraction; HA, hyaluronic acid
  2. aF statistic and p value of the main effect
  3. bF statistic and p value of the crossover effect
  4. *p value < 0.05; **p value < 0.01; ***p value < 0.001; ns, non-significant (p value > 0.05), compared with pre-treatment