Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human umbilical cord-derived mesenchymal stem cells alleviate insulin resistance in diet-induced obese mice via an interaction with splenocytes

Fig. 2

Multiple UC-MSC infusions alleviated insulin resistance and inflammation of epididymal adipose tissue in HFD-fed mice. a Representative H&E staining of epididymal adipose tissue from the Nor, HFD and MSC groups. Scale bar = 100 μm. b The size of adipocytes was evaluated via digital image analysis. c Weight of inguinal adipose tissue. d Weight of epididymal adipose tissue. e Immunoblotting analysis of p-AKT and total AKT expression in epididymal adipose tissue. The ratios of p-AKT to total AKT were quantitated (f). g Real-time polymerase chain reaction analysis of inflammation-related gene expression in epididymal adipose tissue. The results are presented relative to those of normal mice, which were set as 1. Values are the mean ± SD; n = 6 mice per group, *P < 0.05; **P < 0.01

Back to article page