Characteristics of SOX9-positive progenitor-like cells during cholestatic liver regeneration in biliary atresia

Table 1 Comparison of patient characteristics between the fibrosis groups

Variables	CCC Fibrosis stage 0 n = 4	BA Fibrosis stage 1 n = 6	BA Fibrosis stage 2 + 3 n = 12	BA Fibrosis stage 4 n = 6	P value
Demographic data
Age, months	55 ± 28	1.4 ± 0.4	2.2 ± 0.7	5.8 ± 1.1
Male gender, %	0 (0)	3 (50)	3 (50)	2 (33.3)
Laboratory data
DBIL, µmol/L	3.2 ± 0.8	127.5 ± 37.3	128.8 ± 15.5	173.5 ± 66.6	0.005*
ALP, IU/L	228.5 ± 67.8	591.5 ± 189.6	721.6 ± 180.3	431.5 ± 124.9	0.02*
GGT, IU/L	98.2 ± 91.9	191.4 ± 105.4	440.0 ± 319.3	501.7 ± 471.3	0.033*
ALT, IU/L	42.6 ± 32.2	144.7 ± 97.7	155.1 ± 51.4	304.7 ± 137.2	0.003*
AST, IU/L	35.85 ± 15.3	190.5 ± 85.1	242.5 ± 82.5	502.7 ± 229.8	0.001*
TBA, µmol/L	4.5 ± 5.5	77.7 ± 6.9	137.1 ± 65.6	246.8 ± 106.4	0.000*

For the BA sample, 18 specimens were obtained from the Kasai procedure, and 6 specimens were obtained from liver transplantation without Kasai surgery. Four Congenital Choledochal Cyst specimens were collected as controls
*P < 0.05

ISSN: 1757-6512