Table 1 Baseline characteristics

Age (years)

Mean ± SD

53 ± 15.3

61.7 ± 9.7

Gender, n (%)

Female

3 (27.2)

2 (33.3)

Male

8 (72.7)

4 (66.6)

Symptoms, n (%)

Fever

8 (72.7)

5 (83.3)

Cough

9 (81.8)

4 (66.6)

Nausea or vomiting

3 (27.3)

2 (33.3)

Diarrhea

4 (36.4)

0 (0)

Loss of taste or smell

4 (36.4)

3 (50)

Shortness of breath

9 (81.8)

3 (50)

Disorientation and confusion

2 (18.2)

0 (0)

*Oxigenation index (PaO₂/FiO₂) at enrollment, n (%)

Mild

4 (36.4)

5 (83.3)

(200˂PaO₂/FiO₂ ≤ 300 mmHg)

Moderate

6 (54.5)

0 (0)

(100˂PaO₂/FiO₂ ≤ 200 mmHg)

Severe

1 (9.1)

1 (16.6)

(PaO₂/FiO₂ ≤ 100 mmHg)

Interval between symptoms onset and hospital admission (days)

Mean ± SD

6.8 ± 3.2

8 ± 1.6

Interval between symptoms onset and first cell injection (days)

Mean ± SD

10.7 ± 3.9

12.1 ± 2.2

Comorbidities, n (%)

Diabetes

4 (36.4)

3 (50)

Hypertension

6 (54.5)

3 (50)

Kidney disease

1 (9.1)

0 (0)

Chronic obstructive pulmonary

0 (0)

1 (16.7)

Disease

Schizophrenia

1 (9.1)

0 (0)

Obesity (BMI > 30)

6 (54.5)

3 (50)

Concomitant treatment, n (%)

Anticoagulant

11 (100)

6 (100)

Steroids

11 (100)

6 (100)

Antibiotics

2 (18.2)

1 (16.7)

Antiviral drugs

2 (18.2)

0 (0)