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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Comparison of the treatment efficacy of umbilical mesenchymal stem cell transplantation via renal subcapsular and parenchymal routes in AKI-CKD mice

Fig. 3

Assessment of renal function and kidney pathological damage after MSC transplantation via the subcapsular and parenchymal routes. A Experimental design. B Serum creatinine levels in the groups at 3 days after IRI. ***p < 0.001, ANOVA corrected with the Bonferroni coefficient. n = 5–8 mice per group. C Quantitative assessment of tubular damage. **p < 0.01; *p < 0.05, ANOVA corrected with the Bonferroni coefficient. n = 10 fields per mice. D Representative micrographs of PAS staining showing kidney injury in IRI mice after subcapsular and parenchymal MSC transplantation. Asterisks in the enlarged boxed areas indicate injured tubules. Arrows in the enlarged boxed areas indicate regenerative cells

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