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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Comparison of the treatment efficacy of umbilical mesenchymal stem cell transplantation via renal subcapsular and parenchymal routes in AKI-CKD mice

Fig. 5

Differences in the antifibrotic effects of subcapsular and parenchymal MSC transplantation in AKI-CKD mice at 28 days. A Experimental design. B Serum creatinine levels in the groups at 28 days after IRI. ***p < 0.001, ANOVA corrected with the Bonferroni coefficient. n = 4–5 mice per group. C Quantitative assessment of fibrotic areas. **p < 0.01; *p < 0.05, ANOVA corrected with the Bonferroni coefficient. n = 4–5 mice per group. D Representative micrographs showing Masson staining of renal collagen deposition at 28 days after IRI in the various groups as indicated. E Representative micrographs showing PAS staining in the various groups. F Representative immunohistochemical staining of fibronectin in the groups after 28 days of IRI. G Quantitative analysis of the fibronectin-positive areas in the groups after IRI. ***p < 0.001, ANOVA corrected with the Bonferroni coefficient. n = 4–5 per group

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Stem Cell Research & Therapy

ISSN: 1757-6512