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Table 1 Comparison of baseline characteristics between two groups of patients

From: Return to work after cell transplantation in patients with angiitis-induced critical limb ischaemia and factors related: a single-centre retrospective cohort study

 

Total

RTW group

Non-RTW group

P value

 

(n = 171)

(n = 119)

(n = 52)

 

Demographic characteristics

Age, years, mean ± SD

41.9 ± 9.6

40.9 ± 9.8

44.3 ± 8.9

0.033

 20–29, n (%)

23 (13.4)

20 (16.8)

3 (5.8)

0.052

 30–39, n (%)

39 (22.8)

29 (24.4)

10 (19.2)

0.461

 40–49, n (%)

68 (39.8)

43 (36.1)

25 (48.1)

0.142

 50–59, n (%)

41 (24.0)

27 (22.7)

14 (26.9)

0.551

 < 40 years, n (%)

62 (36.3)

49 (41.2)

13 (25.0)

0.043

 ≥ 40 years, n (%)

109 (63.7)

70 (58.8)

39 (75.0)

0.043

Gender, (male/female)

170/1

118/0

51/1

0.131

Body mass index, (kg/m2) (mean ± SD)

23.5 ± 3.2

23.5 ± 3.4

23.7 ± 2.7

0.636

Married, n (%)

160 (93.6)

108 (90.8)

51 (98.1)

0.119

Having children, n (%)

150 (87.7)

101 (84.9)

49 (94.2)

0.099

College education, n (%)

12 (7.0)

10 (8.4)

2 (3.8)

0.283

Occupation

    

 Mental worker, n (%)

41 (30.0)

39 (32.8)

2 (3.8)

0.002

 Manual worker, n (%)

82 (48.0)

52 (43.7)

30 (57.7)

0.092

 Farmer, n (%)

11 (6.4)

6 (5.0)

5 (9.6)

0.262

 Self-employed, n (%)

29 (17.0)

18 (15.1)

11 (21.2)

0.334

 Other, n (%)

8 (4.6)

4 (3.4)

4 (7.7)

0.217

Hometown region

    

 Central, n (%)

26 (15.2)

18 (15.1)

8 (15.4)

0.965

 East, n (%)

124 (72.5)

89 (74.8)

35 (67.3)

0.313

 West, n (%)

21 (12.3)

12 (10.1)

9 (17.3)

0.186

Cardiovascular risk factors

    

 Smoking history, n (%)

141 (82.5)

99 (83.2)

42 (80.8)

0.701

 Hypertension, n (%)

12 (7.0)

8 (6.7)

4 (7.7)

0.819

 Diabetes mellitus, n (%)

12 (7.0)

9 (7.6)

3 (5.8)

0.673

 Hyperlipidaemia, n (%)

15 (8.8)

10 (8.4)

5 (9.6)

0.797

Cause of AICLI

    

 TAO, n (%)

159 (93.0)

112 (94.1)

47 (90.4)

0.379

 Other, n (%)

12 (7.0)

7 (5.9)

5 (9.6)

0.379

Medication history

    

 Antiplatelet drugs, n (%)

104 (60.8)

77 (70.6)

27 (51.9)

0.115

 Vasodilator, n (%)

39 (22.8)

19 (16.0)

13 (25.0)

0.164

 Warfarin/Rivaroxaban, n (%)

18 (10.5)

11 (9.2)

7 (13.5)

0.408

 Anti-infective treatment, n (%)

5 (2.9)

3 (2.5)

2 (3.8)

0.636

Surgical history

    

 Bypass, n (%)

6 (3.5)

4 (3.4)

2 (3.8)

0.874

 Endarterectomy, n (%)

1 (0.6)

0 (0.0)

1 (1.9)

0.129

 Stent grafting, n (%)

8 (4.7)

4 (3.4)

4 (7.7)

0.217

 Balloon angioplasty, n (%)

25 (14.6)

18 (10.5)

7 (13.5)

0.777

 Thrombolysis, n (%)

26 (15.2)

17 (9.9)

9 (17.3)

0.613

 Thrombectomy, n (%)

12 (7.0)

8 (4.7)

4 (7.7)

0.819

 Toe amputation, n (%)

19 (11.1)

13 (10.9)

6 (11.5)

0.906

Blood examination, n (%)

    

 Fibrinogen, mg/dL, (median, IQR)

321.5 (257–408)

307 (244–388)

354 (292–477)

< 0.001

 CRP, mg/L, (median, IQR)

5.4 (1.8–14.8)

4.5 (1.55–11.65)

8.2 (2.3–18.7)

0.022

 Glucose, mmol/L, (median, IQR)

4.7 (4.4–5.2)

4.7 (4.4–5.1)

4.8 (4.6–5.3)

0.915

 GHb, %, (median, IQR)

5.4 (5.2–5.7)

5.45 (5.2–5.7)

5.4 (5.25–5.60)

0.359

 Creatinine, μmol/L, (median, IQR)

71.5 (64–82)

72 (65–82)

71 (63–82)

0.600

 GFR, mL/min, (median, IQR)

107 (99–119)

107 (97–117)

109 (101.5–120)

0.222

 ESR, mm/h, (median, IQR)

14 (7–30)

14.5 (7–32)

13 (6–26)

0.453

  1. The data presented are the numbers (%) and the means ± standard deviations or medians and the interquartile ranges
  2. RTW, return to work; non-RTW, not return to work; SD, standard deviation; AICLI, angiitis-induced critical limb ischaemia; TAO, thromboangiitis obliterans; IQR, interquartile range; CRP, C-reactive protein; GHb, glycosylated haemoglobin; GFR, glomerular filtration rate; ESR, erythrocyte sedimentation rate