Table 5 Therapeutic MSCs-derived Exo-miRs in CRC treatment
Source of exosome | Exo-miR | Molecular target | References |
|---|---|---|---|
Tumor-suppressive MSC-Exo-miRs | |||
hUC-MSCs | miR-3940-5p | ITGA6 | [72] |
hBM-MSCs | miR-22-3p | RAP2B/PI3K/AKT pathway | [82] |
hBM-MSCs | miR‐16‐5p | ITGA2 | [83] |
Tumorigenic MSC-Exo-miRs | |||
hBM-MSCs | miR-424 | TGFBR3 | [97] |
hBM-MSCs | miR-142-3p | Inhibiting the Numb expression and promoting the Notch signaling pathway | [101] |
hCC-MSCs | miR-30a miR-222 | MIA3 | [102] |