Fig. 3From: Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIFThe micro-CT measurement and semi-quantitative analysis of SD rats treated with pure gelatine nanoparticle hydrogel (denoted as GNPs) and exosome-loaded gelatine nanoparticle hydrogel (denoted as GNPs-Exo) implanted in calvarial bone defects. A Micro-CT imaging of calvarial bone at 4 and 8 weeks postoperatively. B–F The new bone formation rate and bone formation-related parameters (BV/TV, Tb.N, Tb.Th, Tb.Sp) were calculated. * P < 0.05, ** P < 0.01 using one-way ANOVA and Student-Newman-Keuls testBack to article page