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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing

Fig. 6

Angiogenesis and antioxidant assays. a Number of formed tubes per well (n = 4). b Diameter length of the formed tubes. c Number of branching points per well. ***p < 0.001 against the control group, # p < 0.05 against the positive control group, N.S. non-significance. d Calcein-stained fluorescence and brightfield images of the formed vessels. Scale bars are 500 µm. e Cell survival under a H2O2-mediated ROS environment (I) after a 2 h pre-treatment with EVs (n = 4), (II) after a 6 h pre-treatment with EVs (n = 4) and (III) under a 4 h co-treatment of cells with EVs and H2O2 (n = 4). **p < 0.005; ***p < 0.001, n.s. non significance against control group, # p < 0.05 between groups

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