Fig. 8

Transcriptome analysis of rd12 mice retina transplanted with cells. A RNA-seq data were analyzed to measure sample distances to evaluate for similarities. Hierarchical clustering was performed using DESeq2, and the data were plotted as a sample-to-sample heatmap. The colored indicator represents sample distances (blue signifies a high correlation). (B-G) Heatmap and volcano plots showing raw z-scores of RNA-seq log2 transformed values of the top DEGs in retina of rd12 vs rd12 + pMSCs (B, E), rd12 vs rd12 + RPCs (C, F), and rd12 + pMSCs vs rd12 + RPCs (D, G). Upregulated and downregulated genes are red and blue, respectively