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Table 1 Characteristics of included studies

From: Stem cell-derived exosomes in the treatment of acute myocardial infarction in preclinical animal models: a meta-analysis of randomized controlled trials

Study Region Type Model Species sex Source Exosome marker Dose Route Therapy time (min) Follow-up (weeks)
Xiao [12] China LAD MI male mice EMSCs miR-125b 0.2 μg/μL IM 30 4
Liu [10] Netherlands LCX MI pig HMSCs N 0.002 μg/μL IV 60 1, 4
Zhang [17] China LAD MI male rat EMSC miR-24 NSI IM 60 1, 4
Huang [15] China LAD MI male mice ADSCs N 5 μg/μL IM 60 4
Sun [18] China LAD MI male rat HMSC miR-873 1 μg/μL IM 0 4
Huang [21] China LAD MI female rat AMSC lncRNA H19 0.1 μg/μL IM 30 4
Liu [20] China LAD MI rat HMSC N 1 μg/μL IM 0 4
Wang [13] China LAD MI male rat HMSC miR-125b 2 μg/μL IV 0 4
Li [16] China LAD MI male rat AMSC miR-301 NSI IM 30 4
Wei [19] China LAD I/R male rat HMSC miR-181a NSI IM 45 1
  1. IM myocardial injection, IV intravenous injection