Stem cell-derived exosomes in the treatment of acute myocardial infarction in preclinical animal models: a meta-analysis of randomized controlled trials

Table 1 Characteristics of included studies

Study	Region	Type	Model	Species sex	Source	Exosome marker	Dose	Route	Therapy time (min)	Follow-up (weeks)
Xiao [12]	China	LAD	MI	male mice	EMSCs	miR-125b	0.2 μg/μL	IM	30	4
Liu [10]	Netherlands	LCX	MI	pig	HMSCs	N	0.002 μg/μL	IV	60	1, 4
Zhang [17]	China	LAD	MI	male rat	EMSC	miR-24	NSI	IM	60	1, 4
Huang [15]	China	LAD	MI	male mice	ADSCs	N	5 μg/μL	IM	60	4
Sun [18]	China	LAD	MI	male rat	HMSC	miR-873	1 μg/μL	IM	0	4
Huang [21]	China	LAD	MI	female rat	AMSC	lncRNA H19	0.1 μg/μL	IM	30	4
Liu [20]	China	LAD	MI	rat	HMSC	N	1 μg/μL	IM	0	4
Wang [13]	China	LAD	MI	male rat	HMSC	miR-125b	2 μg/μL	IV	0	4
Li [16]	China	LAD	MI	male rat	AMSC	miR-301	NSI	IM	30	4
Wei [19]	China	LAD	I/R	male rat	HMSC	miR-181a	NSI	IM	45	1

ISSN: 1757-6512