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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Every road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routes

Fig. 3

The distribution of IMRC-EVs delivered by different routes. a Live animal imaging of NIR fluorescence after IMRC-EV injection via different routes. IMRC-derived EVs were labeled with NIR and injected into normal mice and BLM- induced mice via the IT or IV route. Mice in the control group were injected with equal volumes of normal saline. b Representative images of organs (24 h post-injection) from BLM-induced mice injected i.v. with IMRC-EVs. c, d The change trend of the fluorescence intensity signal at different time points after the injection of NIR-labeled IMRC-EVs via the IT route (c) and IV route (d)

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