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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Every road leads to Rome: therapeutic effect and mechanism of the extracellular vesicles of human embryonic stem cell-derived immune and matrix regulatory cells administered to mouse models of pulmonary fibrosis through different routes

Fig. 4

The effect of IMRC-EVs delivered via the tracheal and intravenous routes on cytokine levels in the acute phase of the BLM-treated mice. Five days after BLM injury, mice were euthanized and cytokine levels in lung lysate were analyzed by ELISA (a–h). Data are represented as the mean ± SD; n = 5. *P < 0.05, **P < 0.01, *** P < 0.001, and ns indicates no difference. TGF-β1 transforming growth factor-β1, IL interleukin, MCP Monocyte chemoattractant protein, TNF-α tumor necrosis factor-α, MIP macrophage inflammatory protein and VEGF vascular endothelial growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512