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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling

Fig. 1

The differential genes and resistance-associated genes in lung cancers tissues vs normal lung tissues. A The Volcano plot for the differential genes at twofold-change in 998 lung cancer tissues compared with 103 normal lung tissues from TCGA database (the blue dot, 189 downregulated genes; the red dot, 105 upregulated genes; p < 0.05). B The heatmap for the 294 differential expression genes at twofold-changes. C The enriched biology process for the 105 upregulated genes. D The enriched cell components for 189 downregulated genes. E The pie chart for classification of the 998 lung cancer patients. F The heatmap for 32 resistant genes in non-treated and treated patients. G The GO analysis of 32 resistant genes

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Stem Cell Research & Therapy

ISSN: 1757-6512