Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling

Fig. 4

EREG promotes chemoresistance of NSCLC. A The EREG expression in non-treated lung cancer patients compared with treated lung cancer patients by RNA-Seq analysis. B, C Kaplan–Meier curves for overall survival (B) and disease-free survival (C) according to EREG expression levels in lung cancer patients. D WB detection of EREG protein level in cisplatin and taxol-treated A549 cells. E The cell viability of A549 cells and H1299 cells treated with 100 ng/mL EREG combined with 100 ng/mL taxol for 48 h, n = 3. F The statistics data of A549 and H1299 spheres treated with 100 ng/mL EREG plus with 100 ng/mL taxol. n = 3. G RT-qPCR detection for the stemness-associated genes in H1299 cells treated with 100 ng/mL EREG. n = 3. *, p < 0.01; **, p < 0.01

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512