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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia–reperfusion injure by restoring CPT1A mediated fatty acid oxidation

Fig. 1

Characterization of EVs. a Schematic diagram of the animal experiment. Briefly, mice were treated with Norm-EVs (100 μg), Hypo-EVs (100 μg) or PBS immediately after surgery and on D 1 postsurgery and were sacrificed at D 2, D 7, and D 14 after surgery. bTransmission electron microscopy image of both analysed EVs. Scale bar represents 200 nm. c Dynamic light scattering measuring the size distribution of both analysed EVs. d Western blot analysed the EVs-specific positive biomarkers (Alix and TSG101) and the negative marker GM130 in the EVs and their parent cell (MSC)

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Stem Cell Research & Therapy

ISSN: 1757-6512