Fig. 4
From: Meniscus repair: up-to-date advances in stem cell-based therapy
Copyright 2021, Li et al. MECM, meniscus extracellular matrix; KGN, kartogenin; PLGA, poly(lactic-co-glycolic) acid; µS, microspheres
Schematic representation of the preparation process of the scaffolds [109]. Flow chart of the preparation of the A MECM gel, B KGN-containing PLGA microspheres, and C PCL/MECM-KGN µS scaffold; D Possible mechanism of meniscus regeneration. Enhanced mechanical strength, endogenous stem cells, and sustained releasing KGN contributed to meniscus regeneration in these experiments. Reproduced under the terms of the CC BY-NC license [109].