Fig. 1

The experimental designed to investigate the influence of the fiber morphology and atorvastatin (ATV) loaded in the fiber on the paracrine secretion function of BMSCs. The scaffolds for cell culture included electrospun fibers (EFs) in random, a mesh-like organization, and the mesh-like organization with atorvastatin loaded in, which were designated as PCL/R, PCL/M and PCL/MAT, and the cultures on EFs were compared to the BMSCs cultured on polystyrene microplate (MP). Then the PCL/MAT membranes seeded with BMSCs were used as the artificial skin in vivo wound healing