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Table 1 Top 20 clusters with representative enriched terms (one per cluster)

From: The role of serum amyloid A1 in the adipogenic differentiation of human adipose-derived stem cells basing on single-cell RNA sequencing analysis

GO

Category

Description

Count

%

Log10(P)

Log10(q)

GO:0050727

GO Biological Processes

Regulation of inflammatory response

10

22.73

− 7.69

− 3.37

GO:0010757

GO Biological Processes

Negative regulation of plasminogen activation

3

6.82

− 6.95

− 2.93

GO:0019216

GO Biological Processes

Regulation of lipid metabolic process

8

18.18

− 6.12

− 2.42

R-HSA-5661231

Reactome Gene Sets

Metallothioneins bind metals

3

6.82

− 6.04

− 2.42

GO:0071407

GO Biological Processes

Cellular response to organic cyclic compound

8

18.18

− 5.26

− 2.27

GO:0001817

GO Biological Processes

Regulation of cytokine production

9

20.45

− 5.14

− 2.20

GO:0015909

GO Biological Processes

Long-chain fatty acid transport

4

9.09

− 5.12

− 2.20

M167

Canonical Pathways

PID AP1 PATHWAY

4

9.09

− 5.09

− 2.19

GO:0034250

GO Biological Processes

Positive regulation of cellular amide metabolic process

5

11.36

− 4.98

− 2.14

R-HSA-8953897

Reactome Gene Sets

Cellular responses to external stimuli

8

18.18

− 4.96

− 2.14

GO:2000379

GO Biological Processes

Positive regulation of reactive oxygen species metabolic process

4

9.09

− 4.43

− 1.83

GO:0051051

GO Biological Processes

Negative regulation of transport

7

15.91

− 4.28

− 1.79

M5884

Canonical Pathways

NABA CORE MATRISOME

5

11.36

− 3.86

− 1.57

hsa04145

KEGG Pathway

Phagosome

4

9.09

− 3.75

− 1.50

GO:0030279

GO Biological Processes

Negative regulation of ossification

3

6.82

− 3.31

− 1.23

GO:0034109

GO Biological Processes

Homotypic cell–cell adhesion

3

6.82

− 3.31

− 1.23

GO:0031348

GO Biological Processes

Negative regulation of defense response

4

9.09

− 2.95

− 0.96

GO:0007098

GO Biological Processes

Centrosome cycle

3

6.82

− 2.81

− 0.86

GO:0002526

GO Biological Processes

Acute inflammatory response

3

6.82

− 2.11

− 0.30

  1. “Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “Log10(P)” is the p value in log base 10. “Log10(q)” is the multi-test adjusted p value in log base 10