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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia

Fig. 6

Tissue-to-air space ratio on PND 7 and 14 (n = 6). A Representative images for H&E staining (PND7). B On PND7, tissue-to-air space ratio was decreased in saline-treated injured group compared to control groups. In contrast to hAEC treatment, only term but not preterm EVs improved lung structure. C On PND14, tissue-to-air space ratio remained lower in saline-treated injured group. Term EV treatment mitigated tissue-to-air space ratio and made it comparable to hAEC treatment group and healthy control group. However, preterm EVs did not improve lung structure. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512