Fig. 2From: The circadian clock has roles in mesenchymal stem cell fate decisiona Both PPARγ and its cofactor PGC-1α serve as master transcription factors in adipogenic differentiation and are tightly regulated by the circadian clock. b miR-7-5p liberates CRY from the BMAL1-CLOCK complex to promote the transcription of P300. P300 and RUNX2 act simultaneously on the targeted promoter. c BMAL1 promotes the expression of SOX9 and PER1 inhibits SOX6 expressionBack to article page