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Table 1 Epigenetic modifying enzymes shared both in the circadian clock and in the MSC fate decisions

From: The circadian clock has roles in mesenchymal stem cell fate decision

Circadian component

Epigenetic regulators

Differentiation signals

References

BMAL1-CLOCK

P300/CBP; miR-7-5p

RUNX2

[66]

REV-ERBα/RORα

HDACs

NF-κB

[104]

SIRT1

SIRT1

PPARγ; RUNX2; SOX9; Wnt/β-catenin

[105]

Bmal1

EZH2

BMP2; ATOH8

[106, 107]

Bmal1

DNMT3

Collagen type II

[108]