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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype

Fig. 5

Magnetic resonance imaging (MRI) detection of labeled integrin α10-MSCs in the synovial fluid. Baseline MRI scans were performed before injection of MIRB-labeled integrin α10-MSCs and at different timepoints after injection. Coronal views of the knee of rabbit #1 before injection (Baseline, A), immediately after (0h, B) and 12 h (12h, C) after injection of 1.3 × 106 MIRB-labeled integrin α10-MSCs. The MSCs are detected as black dots. At baseline the synovial fluid is clear (surrounded by white line). Immediately after injection, MSCs were distributed in the synovial fluid (arrows) (B), and after 12 h they were found lining the synovial membrane (arrows) (C). MIRB Molday Ion conjugated with Rhodamine B

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