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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype

Fig. 7

Magnetic resonance imaging (MRI) signal intensity (SI) in the cartilage defects after homing of labeled integrin α10-MSCs. All images of the same rabbit were aligned. A 3D region of interest (ROI) was marked in the area of the cartilage defect (indicated in Fig. 6) and SI in the ROI was automatically calculated. The graph shows the % drop in SI from baseline. An SI drop indicates accumulation of labeled α10-MSCs in the defect. The SI drop was statistically significant on day 4 (p = 0.036) relative to baseline. Note that rabbit #3 was removed from the study because of unintentional peri-articular injection of labeled α10-MSCs

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Stem Cell Research & Therapy

ISSN: 1757-6512