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Table 2 Percentage of deaths in IVD-studied groups in subacute and subchronic phase

From: Standard toxicity study of clinical-grade allogeneic human bone marrow-derived clonal mesenchymal stromal cells

Groups Number of animals per group Dose levels Mortality (%)
Subacute phase Subchronic phase Subacute phase Subchronic phase
Control 12 (6 males and 6 females) 12 (6 males and 6 females) 50 μl (NS + HA)/disc 0 0
Treatment 12 (6 males and 6 females) 12 (6 males and 6 females) 2.5 × 106 cells/disc in 50 μl (HA + NS) 8.3 (one female) 0
  1. IVD intervertebral disc; NS normal saline; HA hyaluronic acid