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Table 2 Percentage of deaths in IVD-studied groups in subacute and subchronic phase

From: Standard toxicity study of clinical-grade allogeneic human bone marrow-derived clonal mesenchymal stromal cells

Groups

Number of animals per group

Dose levels

Mortality (%)

Subacute phase

Subchronic phase

Subacute phase

Subchronic phase

Control

12 (6 males and 6 females)

12 (6 males and 6 females)

50 μl (NS + HA)/disc

0

0

Treatment

12 (6 males and 6 females)

12 (6 males and 6 females)

2.5 × 106 cells/disc in 50 μl (HA + NS)

8.3 (one female)

0

  1. IVD intervertebral disc; NS normal saline; HA hyaluronic acid