|
Parameters
|
Subacute phase
|
Subchronic phase
|
|---|
|
Treatment group
|
Control
|
P value
|
Treatment group
|
Control
|
P value
|
|---|
|
Number of animals analyzed
|
12
|
12
|
12
|
11
|
|---|
|
Glucose (mg/dl)
|
145.91 ± 7.94
|
151.43 ± 11.68
|
0.19
|
134.33 ± 11.93
|
128.81 ± 13.36
|
0.30
|
|
Urea (mg/dl)
|
54.08 ± 4.96
|
51.08 ± 4.87
|
0.14
|
48.00 ± 5.57
|
49.27 ± 4.45
|
0.55
|
|
Cr (mg/dl)
|
0.65 ± 0.10
|
0.60 ± 0.10
|
0.35
|
0.70 ± 0.09
|
0.76 ± 0.11
|
0.15
|
|
ALT (U/l)
|
49.25 ± 5.18
|
51.08 ± 6.50
|
0.45
|
56.58 ± 6.25
|
55.09 ± 6.26
|
0.57
|
|
AST (U/l)
|
103.50 ± 9.11
|
102.91 ± 10.76
|
0.88
|
101.66 ± 8.65
|
102.36 ± 7.07
|
0.83
|
|
ALP (U/l)
|
519.08 ± 174.52
|
584.44 ± 149.31
|
0.33
|
365.91 ± 109.15
|
324.0 ± 75.54
|
0.30
|
|
Chol (mg/dl)
|
54.16 ± 7.35
|
53.75 ± 7.74
|
0.89
|
51.33 ± 9.80
|
51.09 ± 9.54
|
0.95
|
|
TG (mg/dl)
|
49.91 ± 17.35
|
54.83 ± 20.89
|
0.53
|
70.58 ± 19.03
|
64.81 ± 17.85
|
0.46
|
|
TP (g/dl)
|
6.01 ± .59
|
6.08 ± .74
|
0.81
|
6.21 ± .59
|
6.36 ± .66
|
0.57
|
|
Alb (g/dl)
|
3.42 ± .24
|
3.40 ± .21
|
0.83
|
3.37 ± .26
|
3.38 ± .37
|
0.96
|
|
TB (mg/dl)
|
0.76 ± 0.22
|
0.62 ± 0.18
|
0.09
|
0.18 ± 0.02
|
0.18 ± 0.03
|
0.65
|
|
DB (mg/dl)
|
0.15 ± 0.05
|
0.13 ± 0.04
|
0.26
|
0.10 ± 0.02
|
0.11 ± 0.02
|
0.50
|
|
P (mg/dl)
|
6.58 ± 0.79
|
7.19 ± 0.97
|
0.10
|
5.94 ± 0.29
|
5.99 ± 0.20
|
0.65
|
|
Ca (mg/dl)
|
8.35 ± 0.17
|
8.23 ± 0.31
|
0.27
|
8.09 ± 1.03
|
8.04 ± 0.51
|
0.89
|
|
Na (mEq/l)
|
140.66 ± 2.05
|
140.50 ± 2.11
|
0.84
|
139.16 ± 2.16
|
139.45 ± 1.80
|
0.73
|
|
K (mEq/l)
|
3.91 ± 0.22
|
4.05 ± 0.56
|
0.46
|
3.90 ± 0.27
|
3.65 ± 0.44
|
0.12
|
|
Cl (mEq/l)
|
107.66 ± 4.79
|
106.91 ± 5.35
|
0.72
|
103.83 ± 3.06
|
103.27 ± 3.37
|
0.68
|
|
HDL (mg/dl)
|
41.25 ± 2.83
|
41.08 ± 3.08
|
0.89
|
42.33 ± 2.96
|
41.54 ± 3.11
|
0.54
|
|
LDL (mg/dl)
|
33.00 ± 3.46
|
33.91 ± 2.93
|
0.49
|
33.00 ± 3.33
|
31.81 ± 2.78
|
0.36
|
|
PT (s)
|
17.97 ± 1.40
|
17.81 ± 0.90
|
0.74
|
17.95 ± 0.99
|
17.94 ± 0.96
|
0.97
|
|
PTT (s)
|
36.80 ± 2.76
|
35.97 ± 4.46
|
0.59
|
33.94 ± 2.79
|
33.32 ± 3.12
|
0.62
|
- BM-cMSC bone marrow-derived mesenchymal stromal cells; IV intravenous; Cr creatinine; ALT alanine aminotransferase; AST aspartate transaminase; ALP alkaline phosphatase; Chol cholesterol; TG triglycerides; TP total protein; Alb albumin; TB total bilirubin; DB direct bilirubin; P phosphorus; Ca calcium; Na sodium; K potassium; CL chloride; HDL high-density lipoprotein cholesterol; LDL low-density lipoprotein cholesterol; SD standard deviation. P ≤ 0.05 indicates statistical significance
