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Table 4 Follow-up feedbacks of patients after nebulization treatment

From: Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study

 

Days from the onset of nebulization treatment

Clinical Symptoms

COVID-19 antibody test

Lymphocyte count

Alanine aminotransferase (ALT) (U/L)

Creatinine (Cr) (μmol/L)

Chest CT images

Patient 1

Day 20

Denied

IgM ( −), IgG ( −)

2.29 × 109/L

N/A

N/A

Obvious absorption of infiltration at both lobes compared with the day of symptom onset

Day 36

Denied

N/A

N/A

N/A

N/A

Slight absorption compared with Day 20

Patient 2

Day 41

Denied

IgM ( −), IgG ( +)

2.14 × 109/L

45

53

Partial absorption of infiltration compared with the day of symptom onset

Patient 3

Day 22

Denied

N/A

N/A

N/A

N/A

Normal

Day 59

Denied

N/A

3.72 × 109/L

9

63

Normal

Patient 4

Day 17

Mild cough

N/A

N/A

N/A

N/A

Infiltration at both lobes, similar to the day of symptom onset

Day 43

Denied

N/A

N/A

N/A

N/A

Infiltration at both lobes, similar to Day 17

Patient 5

Day 36

Denied

IgM ( −), IgG ( +)

2.52 × 109/L

20

55

Slight absorption compared with the day of symptom onset

Patient 6

Day 24

Mild cough

N/A

N/A

N/A

49

N/A

Patient 7

Day 28

Denied

IgM ( −), IgG ( +)

1.82 × 109/L

10

50

Obvious absorption of infiltration at both lobes compared with Day 2

Day 52

Denied

N/A

1.97 × 109/L

N/A

N/A

Slight absorption compared with Day 28