Fig. 2

a Prognostic stemness network landscape of 13 prognostic stemness gene sets interactions, lineages and their impacts on OS for CRC patients. The size of each gene set represents its prognostic impact by log-rank test. Skyblue dots indicate favorable variables and black dots represent risk factors. The red lines connecting stemness gene sets indicate positive Spearman correlations, and the blue lines are negative correlations, and the thickness of the lines represents the Spearman correlation strengths. b Consensus clustering identified three distinct clusters of CRC with different stemness gene sets enrichment scores. c Heatmap depicting the landscape of ssGSEA stemness scores in three clusters. d Box plot displaying the differences of 26 ssGSEA stemness scores between the three clusters by Kruskal–Wallis test.  ***P < 0.001. e Kaplan–Meier OS curves for CRC patients between different stemness subtypes. f Box plot showing the differences of 22 infiltrating immune cells, stromal and immune scores between the three clusters by Kruskal–Wallis test. ns, not significance, ∗P < 0.05, ∗∗P < 0.01,  ***P < 0.001. OS, overall survival; CRC, colorectal cancer