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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Intramyocardial injected human umbilical cord-derived mesenchymal stem cells (HucMSCs) contribute to the recovery of cardiac function and the migration of CD4+ T cells into the infarcted heart via CCL5/CCR5 signaling

Fig. 2

HucMSCs administration improved cardiac function of mice post MI injury. A The flow diagram of the experiment design. The two groups: MI-N.S and MI-HucMSC. After MI injury was established, mice were immediately injected N.S or HucMSCs by three points into the peri-infarcted heart zone. B Representative echocardiographic images (M-mode) in two groups on day 7 following MI surgery. C Statistical results of cardiac function on day 7 between MI-N.S and MI-HucMSC groups (n = 13 per group). D Representative echocardiographic images (M-mode) in two groups on day 28. E Statistical results of cardiac function on day 28 between MI-N.S and MI-HucMSC groups (n = 13 per group) following MI surgery. *p < 0.05 versus MI-N.S group. LVEF left ventricular ejection fraction; LVFS left ventricular fractional shortening; LVEDV/LVESV left ventricular end diastolic/systolic volume; LVEDD/LVESD left ventricular end diastolic/systolic diameter

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