Fig. 5

Cdc42 regulates activin B-induced ADSCs-mediated neovascularization and wound contraction in vivo. A Representative photomicrographs of CD 31 immunohistochemical staining treated with PBS, activin B, ADSCs, activin B+ADSCs, ADSCs (Cdc42N17), and activin B+ADSCs (Cdc42N17), respectively, at the specified time. The black arrow indicates positive staining of CD31. Scale bars = 200 μm. B Representative photomicrographs of α-SMA immunohistochemical staining of wounds per group on days 3 and 7 after wounding. Scale bars = 200 μm. The areas stained with α-SMA were determined by planimetric image analysis using Image-Pro Plus 6.0 software. All values are expressed as mean ± SD from three independent repeats, *P < 0.05