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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Activin B-activated Cdc42 signaling plays a key role in regulating adipose-derived mesenchymal stem cells-mediated skin wound healing

Fig. 7

Cdc42 regulates activin B-induced ADSCs transcriptional signature. A Heatmap showing differentially expressed genes (DEGs) between activin B+ADSCs and activin B+ADSCs (Cdc42N17). There were 355 upregulated (Red) and 615 (Blue) downregulated DEGs in activin B+ADSCs (Cdc42N17), respectively, and were subjected to Kyoto Encyclopedia of Genes and Genomes pathways (KEGG) enriched and gene ontology (GO) functional enrichment analysis. B and C showing the genes top 15 enrich pathway, while D showing the top 15 GO terms in upregulated and downregulated DEGs. E Selected gene expression in some of the GO terms. F qPCR analysis of relative expression level of Bmp6, Nkd1, Cd248, Id4, and Sox11 in Act B+ADSCs (Cdc42N17). All values are expressed as mean ± SD from three independent repeats. *P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512