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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK/ERK signaling

Fig. 3

The effect of hucMSCs on diabetes-induced histopathological alterations of aorta endothelium. A HE staining of aortic morphology (100 × and 400 ×), and B aortic endothelial thickness. C, D The representative images (100 × and 400 ×) of immunohistochemical staining of p-ERK and the average optical density values of p-ERK. E and F The representative images (100 × and 400 ×) of immunohistochemical staining of HH3 and the average optical density values of HH3. (data were mean ± SD). **P < 0.01 versus control, #P < 0.05 and ##P < 0.01 versus model

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Stem Cell Research & Therapy

ISSN: 1757-6512